Machine learning-based radiomic evaluation of treatment response prediction in glioblastoma

M Patel, J Zhan, K Natarajan, R Flintham, N Davies… - Clinical radiology, 2021 - Elsevier
… of glioblastoma treatment response will benefit patients and … that act as biomarkers of
treatment effectiveness are required. … An ADC map was calculated for each patient with a b-value …

[HTML][HTML] High-grade glioma treatment response monitoring biomarkers: a position statement on the evidence supporting the use of advanced MRI techniques in the …

OM Henriksen, M del Mar Álvarez-Torres… - Frontiers in …, 2022 - frontiersin.org
treatment, “monitoring biomarkers” are measured serially and are required to detect any change
in the extent of glioma infiltration or provide evidence of treatment response (… rCBV maps

Quantitative CEST and MT at 1.5 T for monitoring treatment response in glioblastoma: early and late tumor progression during chemoradiation

RW Chan, H Chen, S Myrehaug, EG Atenafu… - Journal of Neuro …, 2021 - Springer
… BRAIN-RANO response criteria for high-grade gliomas [29]. … asymmetry maps at 1.5T are
visually distinct between patients… seen over the course of therapy. In Supplementary Fig. S5, it …

[HTML][HTML] Intravoxel incoherent motion (IVIM) modeling of diffusion MRI during chemoradiation predicts therapeutic response in IDH wildtype glioblastoma

PJ Maralani, S Myrehaug, H Mehrabian… - Radiotherapy and …, 2021 - Elsevier
… hence, represents a surrogate of treatment resistance. This hypothesis is … maps in patients
with Grade 3 and 4 gliomas before and midway through radiotherapy, and found that patients

Identifying recurrent malignant glioma after treatment using amide proton transfer-weighted MR imaging: a validation study with image-guided stereotactic biopsy

S Jiang, CG Eberhart, M Lim, HY Heo, Y Zhang… - Clinical Cancer …, 2019 - AACR
… from treatment effect following therapy for malignant gliomastherapies or to premature
termination of effective therapies. … using the determined B 0 map from the water saturation shift-…

Novel Magnetic Resonance Imaging and Positron Emission Tomography in the RT Planning and Assessment of Response of Malignant Gliomas

D Kamson, C Tsien - Molecular Imaging, 2021 - Elsevier
… in malignant gliomas and improve patient outcome [45]. … in order to provide metabolic maps
to neurosurgeons and … prognostication of patient outcome and glioma treatment response. …

Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells

X Wang, K Yang, Q Wu, LJY Kim, AR Morton… - Science translational …, 2019 - science.org
… We interrogated the TCGA glioma database, mapping these and other mutations against
expressions of pyrimidine synthetic enzymes and the KEGG pyrimidine metabolism signature. …

Assessing treatment response of glioblastoma to an HDAC inhibitor using whole-brain spectroscopic MRI

SS Gurbani, Y Yoon, BD Weinberg, E Salgado… - Tomography, 2019 - mdpi.com
response and assess treatment effect on whole brain. This study highlights the potential of
belinostat to be a synergistic therapeutic agent in the treatment of gliomas. … metabolite maps

Regorafenib CSF penetration, efficacy, and MRI patterns in recurrent malignant glioma patients

PS Zeiner, M Kinzig, I Divé, GD Maurer… - Journal of Clinical …, 2019 - mdpi.com
… Furthermore, we analyzed apparent diffusion coefficient (ADC) maps derived from …
treatment response to REG was poor in our cohort of patients with late-stage malignant gliomas

Perfusion MRI-based fractional tumor burden differentiates between tumor and treatment effect in recurrent glioblastomas and informs clinical decision-making

M Iv, X Liu, J Lavezo, AJ Gentles… - American Journal …, 2019 - Am Soc Neuroradiology
treatment effect from tumor in recurrent glioblastomas. Fractional tumor burden maps can
also … An important challenge in the care of patients with high-grade gliomas (HGGs) following …